A New Therapeutic Applications for Drug Repositioning on the Cloud Computing

G Geetharamani¹, M Padma², J ArunPandian³

^1,2,3Anna University, Tiruchirappalli

Abstract

Market pressures and reassess their current drug development model drugs by pharmaceutical companies to tap into new and innovative business models that have driven. Converter is used in medicine as a variety of techniques lend themselves to distributed computing model. Cloud optimizes resource usage and various pilot projects into pharmaceutical companies that reflect the current trend of a computer model. Widespread adoption of cloud security and data provenance drug Converter is the biggest challenge. Drug discovery and development are a time-consuming, expensive and risky venture. As an alternative approach, the pharmaceutical companies, the relatively low cost of failure risks in order to accelerate the drug discovery and development process of repositioning the drug (the drug Repurposing, drug re-profiling, drug review process, treatment modification) approach reduced. Drug repositioning existing drugs / pro-drugs / biologics process of developing a new symptom is a superb strategy to maximize the value of the optimal potential as a therapeutic drug. In other words, rather than an alternative to the drugs or other disease-diseases by targeting the sale of new drugs that are useful in explaining a part of a balanced biological Converter can be bypassed when compared to traditional drug discovery, drug discovery and development, common in many phases of de novo cost, risk and time -reduced has many advantages. Data mining, bioinformatics, and a variety of techniques including the use of novel screening platforms have been used for screening for the identification of potential candidates to replace. According to experts, Efficacy end points have the opportunity to meet with the same success as the original drug. Also, they are not without risks of original drugs. FDA's 505 (b) (2) approval to change the route and marketing allows companies to offer improved safety and efficacy of drugs will be able to reposition. Drugs can also be repositioned to provide the tools and understanding needed to create second-generation drugs. In the end, a large number of patients with a wide range of conditions and regulatory approval process to go through at least once and have an abundance of human experience that can benefit from such drugs. In various ways, such as disease or cancer drugs targeting other complex diseases (eg, obesity, rare diseases), drug converter can provide a good opportunity to have a goal. Drug repositioning technology experts have the opinion that better coordination of research in the next decade Pharma.

Keywords

• Drug Repositioning, in silico, Rare Disease, Drug Repurposing, High-Throughput Screening, Off-Target Drug Repositioning, On-target Drug Repositioning

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Cite this Article as Follows

Geetharamani G, Padma M, ArunPandian J. A New Therapeutic Applications for Drug Repositioning on the Cloud Computing. International Conference on Inter Disciplinary Research in Engineering and Technology 2015. Vol. 1. Chennai: Association of Scientists, Developers and Faculties, 2015. 119-129. Print.